Abraham Lopez
Cambridge
Summary
Skilled in managing and conducting complex research projects across diverse scientific disciplines. Possess strong analytical abilities, adept at data collection, analysis, and interpretation to drive project objectives. Demonstrated capacity for critical thinking and problem-solving to advance scientific understanding and application. Contributed to significant improvements in research methodology and efficiency in previous roles, enhancing overall project outcomes.
Overview
4
4
years of professional experience
Work History
Research Assistant III in the Benitez Lab
Beth Israel Deaconess Medical Center
Boston
09.2023 - Current
- Applied experimental techniques, including immoralized cell culture, iPSC-derived neurons culture, transfection, transduction, transformation, PCR, and immunoassays.
- Processed over 200 human biospecimens for proteomics, metabolomics, and genomics.
- Informed and consented subjects for participation in the neurology biorepository at BIDMC.
- Ensured accurate entry of subject information into data storage software.
- Aided in the development of standard operating procedures for neurology biorepository.
- Ensure lab safety as the lab safety officer of the lab
Research Assistant II in the Hubert Lab
Case Western Reserve University
Cleveland
05.2023 - 08.2023
- Investigated glioblastoma drug resistance using 2D cultures and patient-derived organoids.
- Tested tumor response through combination therapies and cell viability assays.
Undergraduate Researcher in the Hubert Lab
Cleveland Clinic Lerner Research Institute
Cleveland
08.2022 - 05.2023
- Evaluated Bone-Marrow Tyrosine Kinase (BMX) as a biomarker for Ibrutinib in glioblastoma.
- Transfected cells to overexpress and knockdown BMX, assessing resistance to Ibrutinib.
Broad Summer Research Program Student in the Hacohen Lab
Broad Institute of MIT and Harvard
Boston
06.2022 - 08.2022
- Used an enzyme that upon binding to cancer cell biomarker, it adds biotin molecules around the cell surface that can be used as target for drug delivery.
- Gained experience with melanoma cell culture, cloning, protein expression and purification, and flow cytometry.
- Enhanced science communication skills through participation in seminars focused on leadership and collaboration.
Student Research Program in the Robson Lab
Jackson Laboratory Genomic Medicine
Farmington
06.2021 - 08.2021
- Investigated the role of the ELF3 gene in trophoblast cell differentiation using human induced pluripotent stem cells.
- Applied RT-PCR, qPCR, stem cell culture, and immunofluorescence staining to assess the role of the ELF3 gene.
Education
B.S - Neuroscience
Case Western Reserve University
Cleveland, OH05.2023
Skills
- Mammalian and organoid culture
- Induced pluripotent stem cell (iPSC) culture
- Lentiviral transduction
- Transfection techniques
- Flow cytometry analysis
- Research design
- Quantitative PCR (QPCR)
- Molecular cloning
- Immunofluorescence staining
- DNA and RNA extraction
- GraphPad Prism proficiency
- Laboratory safety
- Biospecimen processing
- Data analysis
- Immunoassays
- Microsoft Excel, Word, and PowerPoint
- FIJI image processing
- CellProfiler analysis
- Project management skills
- Scientific communication
- Critical thinking abilities
- Bilingual communication (English/Spanish)
Timeline
Research Assistant III in the Benitez Lab
Beth Israel Deaconess Medical Center
09.2023 - Current
Research Assistant II in the Hubert Lab
Case Western Reserve University
05.2023 - 08.2023
Undergraduate Researcher in the Hubert Lab
Cleveland Clinic Lerner Research Institute
08.2022 - 05.2023
Broad Summer Research Program Student in the Hacohen Lab
Broad Institute of MIT and Harvard
06.2022 - 08.2022
Student Research Program in the Robson Lab
Jackson Laboratory Genomic Medicine
06.2021 - 08.2021
B.S - Neuroscience
Case Western Reserve University
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