Summary
Overview
Work History
Education
Skills
Publications
Languages
Posters
Timeline
Generic

Samantha J. Choi

Brookline

Summary

Highly motivated scientist with 8 years of laboratory experience and currently managing an academic lab. Extensive background in the fields of immunology and microbiology. Committed to collaboration and teamwork to achieve success in biomedical science. Passionate about uncovering the disease mechanisms and contributing to the development of innovative therapeutic strategies.

Overview

9
9
years of professional experience

Work History

Laboratory Manager, Research Assistant III

Harvard Medical School
Boston
01.2021 - Current
  • Department of Immunology, Isaac Chiu Laboratory
  • Managed laboratory operations and ensured compliance with safety regulations.
  • Trained and supervised laboratory staff on standard operating procedures.
  • Coordinated research projects and allocated resources effectively.

Laboratory Manager, Research Assistant II

Harvard Medical School
Boston
01.2020 - 01.2021
  • Department of Immunology, Isaac Chiu Laboratory
  • Managed daily laboratory operations to ensure compliance with safety standards.
  • Supervised staff and coordinated training programs for new employees.
  • Developed and implemented laboratory protocols and procedures for efficiency.

Research Assistant I

Harvard Medical School
Boston
01.2019 - 01.2020
  • Department of Immunology, Isaac Chiu Laboratory
  • Conducted literature reviews to support ongoing medical research projects.
  • Assisted in data collection and analysis for clinical studies.
  • Maintained laboratory equipment and ensured compliance with safety protocols.

Undergraduate Research Assistant

Harvard Medical School
Boston
01.2018 - 01.2019
  • Department of Immunology, Isaac Chiu Laboratory
  • Conducted literature reviews to support ongoing research projects at a prestigious medical institution.
  • Assisted in data collection and management using specialized software for research analysis.
  • Collaborated with faculty members to design experiments and develop research protocols.

Research Intern and Laboratory Assistant

CNP Cosmetics
Seoul
06.2017 - 08.2017
  • Worked in Research and Development department as a lab assistant. Making new cosmetics (lotions, sun’s
    cream, etc) in lab and worked on clinical tests. Making chemical solutions and measuring compounds. Also
    worked on bacterial culturing.

Education

Master of Liberal arts - Extension studies – Biology

Harvard University
Cambridge, MA
05.2026

B.S. - Medical and Molecular Biology

Massachusetts College of Pharmacy And Health Sciences (MCPHS) University
Boston, MA
05.2019

Skills

  • Bacterial culture
  • In vitro and in vivo tissue bacterial load analyses
  • In vivo epicutaneous and subcutaneous bacterial skin infection models
  • Flow cytometry
  • ELISA
  • Mammalian Cell culture
  • SH-SY5Y
  • Human iPSC
  • Cortical neuron differentiation using NGN2 system
  • Analysis of itch and pain behavior
  • PCR
  • Gel electrophoresis
  • RNA extraction from animal tissues
  • Mouse husbandry
  • Cardiac puncture
  • Transcardial perfusion
  • Injections
  • Tissue dissections
  • Cryosection
  • Immunohistology
  • Graph Pad Prism
  • Adobe Photoshop
  • FlowJo
  • FIJI
  • Microsoft Office

Publications

  • Choi, S., Ada, E., Pinho-Ribeiro, F. A., Blake, K. J., Subramaniam, S. R., Baral, P., Held, K. S., Vazquez-Cintron, E. J., Broide, R. S., Brideau-Andersen, A. D., Chiu, I. M., Deng, L., Botulinum Neurotoxin A Enhances Recovery from Bacterial Skin Infections., Manuscript under review.
  • Zhang, J., Pan, T. Y., Kley, A. L., Rajmalani, B. A., Williams, J. B., Lefevre, M. A., Fu, X., Zhan, Q., Deng, L., Jia, Y. Y., Deans, K., Yan, Y., Zhai, Y., Erdogan, O., Choi, S., Wong, C., Atwood, S. X., Clark, R. A., Chiu, I. M., Kupper, T. S., CGRP–Ramp1 Signaling Tunes Memory CD8 T Cell Response through Langerhans Cells., Manuscript under review.
  • Leyva-Castillo, J. M., Vega-Mendoza, D., Strakosha, M., Deng, L., Choi, S., Miyake, K., Karasuyama, H., Chiu, I. M., Phipatanakul, W., Geha, R. S., Basophils are important for the development of allergic skin inflammation., The Journal of allergy and clinical immunology, https://doi.org/10.1016/j.jaci.2024.01.022, Advance online publication., 01/24
  • Deng, L., Costa, F., Blake, K. J., Choi, S., Chandrabalan, A., Yousuf, M. S., Shiers, S., Dubreuil, D., Vega-Mendoza, D., Rolland, C., Deraison, C., Voisin, T., Bagood, M. D., Wesemann, L., Frey, A. M., Palumbo, J. S., Wainger, B. J., Gallo, R. L., Leyva-Castillo, J. M., Vergnolle, N., Chiu, I. M., S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis., Cell, 186, 24, 5375–5393.e25, https://doi.org/10.1016/j.cell.2023.10.019, 10/23
  • Pinho-Ribeiro, F. A., Deng, L., Neel, D. V., Erdogan, O., Basu, H., Yang, D., Choi, S., Walker, A. J., Carneiro-Nascimento, S., He, K., Wu, G., Stevens, B., Doran, K. S., Levy, D., Chiu, I. M., Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion., Nature, 615, 7952, 472–481, https://doi.org/10.1038/s41586-023-05753-x, 10/23
  • Yang, D., Jacobson, A., Meerschaert, K. A., Sifakis, J. J., Wu, M., Chen, X., Yang, T., Zhou, Y., Anekal, P. V., Rucker, R. A., Sharma, D., Sontheimer-Phelps, A., Wu, G. S., Deng, L., Anderson, M. D., Choi, S., Neel, D., Lee, N., Kasper, D. L., Jabri, B., Chiu, I. M., Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection., Cell, 185, 22, 4190–4205.e25, https://doi.org/10.1016/j.cell.2022.09.024, 09/22

Languages

  • English
  • Korean
  • Japanese (intermediate level)

Posters

  • Botulinum neurotoxin accelerates the resolution of bacterial skin infections in mice., Synaptogenesis RA symposium, 09/23, Harvard Medical School
  • Botulinum neurotoxin accelerates the resolution of bacterial skin infections in mice., Immunology Department retreat, 06/23, Harvard Medical School
  • Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314., Communication in the biological sciences, 03/19, MCPHS University

Timeline

Laboratory Manager, Research Assistant III

Harvard Medical School
01.2021 - Current

Laboratory Manager, Research Assistant II

Harvard Medical School
01.2020 - 01.2021

Research Assistant I

Harvard Medical School
01.2019 - 01.2020

Undergraduate Research Assistant

Harvard Medical School
01.2018 - 01.2019

Research Intern and Laboratory Assistant

CNP Cosmetics
06.2017 - 08.2017

Master of Liberal arts - Extension studies – Biology

Harvard University

B.S. - Medical and Molecular Biology

Massachusetts College of Pharmacy And Health Sciences (MCPHS) University
Samantha J. Choi